Research in Diabetes
(Worldwide Studies)
Diascan Study

This was a study carried out across Canada in family practitioners offices. It involved glucose testing in the office and demonstrated that 16% of Canadians over 40 presenting in a physicians office are Diabetic and that half of the Diabetics are undiagnosed. The study showed that the burden of disease in the Diabetic is far higher than the incidence of the disease. The results of the study have been published by Dr. L. Leiter, the principal investigator.

Rosiglitazone Study

This was a study of patients with Type 2 Diabetes who had not achieved control of diabetes despite maximal doses of conventional medications. With the introduction of the newly approved drug of the Thiazolidene class of insulin sensitizer, most patients were able to achieve optimal glucose goals. This study was entirely funded by the Diabetes Clinic without outside assistance and the results were published in the June 2001 issue of DIABETES (supplement), the patients involved were from our clinics in Smiths Falls, ON and Hawkesbury, ON. Results were presented at the 2001 meeting of the American Diabetes Assoc and at the Oct 2001 annual meeting of the Canadian Diabetes Assoc. This study was significant in that it demonstrated the potential of this new class of drug for Type 2 patients who had run out of treatment options and were facing insulin treatment.

Pioglitazone Study

This is an observational study which has demonstrated the safety and efficacy of Pioglitazone, a newly released drug in Canada for treatment of Type 2 Diabetes with insulin resistance. The study showed that the glucose controlling effect of Pioglitazone is equivalent to that of Roziglitazone and proved drug safety. This study is ongoing although recruitment is almost complete. Further analysis will concentrate on the effect of this drug on lipid levels. This was a study funded entirely by the Diabetes Clinic without outside help and was carried out on patients from Smiths Falls and Hawkesbury, Ont. Results are being prepared for presentation.

Insulin Pump Study

This study entitled Option or Essential Tool? Insulin Pump Therapy in Young Women was carried out in our Trenton Clinic and Smiths Falls Clinic in association with Jill Milliken R.N., C.D.E. and demonstrates the benefits of Insulin Pump Therapy for the unique problems of young women with Type 1 Diabetes. This study will be published in the June 2002 issue of DIABETES and will be presented at the American Diabetes Assoc. annual meeting in San Francisco in June 2002.

Telmisartan Study

This study completed in 2001 was an international study on the efficacy and safety of Telmisartan a member of the Ace Receptor Blocker class of Drugs. The results are currently being analyzed.