Lipids & Cardiovascular disease
Effect of Intensive Lipid Lowering on Progression of Coronary Atherosclerosis:
Evidence for an Early Benefit from the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) Trial.
Primary Prevention of Cardiovascular Disease With Atorvastatin in Type 2 Diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS):
Multicentre Randomised Placebo-Controlled Trial
Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes:
the Treating to New Targets (TNT) study
INTERHEART:
A Global Case-Control Study of Risk Factors for Acute Myocardial Infarction
Multifactorial Intervention and Cardiovascular Disease in Patients with Type 2 Diabetes
Insulin Resistance and Cardiovascular Events With Low HDL Cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT)
Renal Function as a Predictor of Outcome in a Broad Spectrum of Patients With Heart Failure [pdf]
Blood pressure & Renal Function
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
Type 2 Diabetes Treatment
Commentary on the Results and Clinical Implications of the PROactive Study
PROACTIVE STUDY: Pioglitazone Protects Against MI, Stroke, Death in High-Risk Type 2 Diabetics
Combined Rosiglitazone & Fenofibrate treatment of Type 2 diabetes leads to improved control with less fluid retention Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial
Type 1 Diabetes Treatment
Diabetes Control and Complications Trial (DCCT)
Prevention of Diabetes
DREAM Trial, Rosiglitazone in diabetes prevention [pdf]
XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial