Avandamet
(Avandia [Rosiglitazone] plus Metformin
?
What is Avandamet:
Avandamet contains a combination of metformin and rosiglitazone, two oral diabetes medicines that help control blood sugar levels. Avandamet works by decreasing the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce. Avandamet is for people with type 2 diabetes who do not use daily insulin injections. This medication is not for treating type 1 diabetes.

Important information about Avandamet
Taking Avandamet may increase your risk of serious heart problems, such as heart attack or stroke. Therefore, Avandamet is available only to certain people with type 2 diabetes that cannot be controlled with other diabetes medications. You should not use Avandamet if you are allergic to metformin (Glucophage) or rosiglitazone (Avandia), or if you advanced heart failure, kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking Avandamet.

Avandamet side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect. Low blood glucose level (hypoglycemia).

Disturbances of the stomach, such as diarrhea, constipation, nausea, vomiting or abdominal pain.
Excessive fluid retention in the body tissues, resulting in swelling (edema).
Weight gain.
Changes in appetite.
Headache.
Heart failure.
Liver disorders.

Avandamet may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or irregular heart rate, dizziness, or feeling very weak or tired.

Get emergency medical help if you have any of these signs of an allergic reaction to Avandamet: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any other serious side effects.