Aggrenox
(Dipyridamole)
Boehringer Ingelheim
About Aggrenox

Aggrenox is a combination of dipyridamole and acetylsalicylic acid (ASA) in an extended release dry powder capsule. Aggrenox can only be obtained with a prescription from your doctor.
 
Aggrenox is not interchangeable with the individual components of ASA and dipyridamole.
 
Why Has Your Doctor Prescribed Aggrenox Capsules? 

Aggrenox capsules are prescribed to help prevent a stroke in people who have had a prior stroke or a transient ischemic attack (TIA). Aggrenox works by preventing the early formation of blood clots.
 

What Is Stroke? 

Stroke is caused by the interruption of the blood supply to the brain and often results in brain damage. A stroke can affect people in different ways. The damage caused by a stroke can affect your senses, your ability to move, your speech, your ability to understand speech, how you behave, how you think, and your memory.
 
What Is Transient Ischemic Attack (TIA)? 

Transient Ischemic Attack is a temporary interference with blood supply to the brain. The symptoms of TIA include dizziness, lightheadedness, numbness, and difficulty swallowing. They may last for only a few minutes or several hours.
 
What You Should Tell Your Doctor Before Taking Aggrenox Capsules

  • if you are pregnant or intend to become pregnant
  • if you are breast-feeding
  • if you are consuming alcoholic beverages
  • if you have any other health problems, including anemia, liver disease, renal disorders, asthma, allergic rhinitis, nasal polyps, history of stomach or duodenal ulcers, bleeding disorders, heart disease, gout, and abnormal menstruation or gynecological bleeding. ASA can increase the risk of hemorrhage, at very low doses, and even several days after the administration. Please let your physician, surgeon, anesthetist or your dentist know if surgery, even minor, is warranted
  • if you are taking any other medication including any other medication you can buy without a prescription
  • if you are taking antidiabetic medicine
  • if you are allergic (such as skin rash or asthma) to any of the components of this drug, including ASA (Aspirin)

Before Taking Aggrenox Capsules, Please Remember

  • Aggrenox has been prescribed for you. Do not  give it to anyone else, even if you think they have the same condition as you. If any other person accidentally ingests Aggrenox, please contact a doctor.
  • Do not  take any other medication unless your doctor tells you to. Be sure to tell any other  doctor, dentist, or pharmacist that you speak to that you are using Aggrenox.
  • Like any other drug product, Aggrenox may cause unwanted effects, such as headache, along with good effects. If you do experience any unusual or unwanted effects while you are using Aggrenox, you should contact your doctor.
  • Consult your doctor immediately if you experience any of the following:
    • stomach pain
    • heartburn
    • nausea
    • vomiting
    • diarrhea
    • skin rash
    • dizziness
    • blood discharge in the mouth
    • black stools 
  • Aggrenox contains ASA (Aspirin) . You should not take Aggrenox at the same time as the following medications withoutthe advice of your doctor:
    • any other medications containing ASA (Aspirin)  
    • other blood thinners (e.g., warfarin or heparin)
    • nonsteroidal anti-inflammatory drugs (NSAIDs)
    • methotrexate
    • drugs affecting gout

How Do You Take Aggrenox Capsules? 

The recommended dosage is 1 capsule twice daily, once in the morning and once in the evening, with or without food. The capsules should be swallowed whole without chewing. Aggrenox is for use in adults only.
 
What You Should Do in Case of Overdosage 

Do not exceed the recommended dosage of Aggrenox. If you accidentally take too many capsules, you should get medical help immediately, either by calling your doctor or by going to the nearest hospital. Always take the labelled medicine container with you whether or not there are any Aggrenox capsules remaining. Symptoms of overdosage, especially in the elderly patients are: ear buzzing, sensation of decreased hearing acuity, and headaches.
 
What Do Aggrenox Capsules Contain? 

Each capsule contains yellow extended release pellets of dipyridamole 200 mg and a round, white tablet of ASA 25 mg.
 
Nonmedicinal Ingredients: 

  • acacia
  • aluminium stearate
  • colloidal silicon dioxide
  • cornstarch
  • dimethicone
  • hydroxypropyl methylcellulose
  • hydroxypropyl methylcellulose phthalate
  • lactose monohydrate
  • methacrylic acid copolymer
  • microcrystalline cellulose
  • povidone
  • stearic acid
  • sucrose
  • talc
  • tartaric acid
  • titanium dioxide
  • triacetin 

Capsule shell contains gelatin, red iron oxide and yellow iron oxide, titanium dioxide and water.

How to Store Aggrenox Capsules

  • Aggrenox capsules must be kept out of the reach of children.
  • Aggrenox should be stored at room temperature (15 to 30°C). Keep Aggrenox in the sealed container provided by your doctor or pharmacist, and protect from excessive moisture.
  • The expiry date of this medicine is printed on the label. Do not use the medicine after this date has passed.